Dr. Liu (February, 2012)
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Dr. Liu is a full professor in the School of Health Sciences. Over the last several years, he has established a productive program at Purdue University in the area of molecular imaging and radiopharmaceutical sciences. Dr. Liu’s research interests include the receptor-based radiotracers for tumor imaging, and development of new radiotracers for myocardial perfusion imaging. Since joining Purdue in 2002, Dr. Liu has been developing small biomolecules as “vehicles” to carry a diagnostic radionuclide to the tumor cells, allowing for monitoring the tumor biological changes at the molecular level. Dr. Liu has become one of the leaders in radiolabeled cyclic RGD peptides as integrin αvβ3-specific SPECT and PET radiotracers for imaging the integrin expression αvβ3 in rapidly growing and metastatic tumors. Recently, Dr. Liu’s group discovered a new 64Cu radiotracer method to localize in the MDR- and MRP-negative tumors with unprecedented high tumor selectivity.
Dr. Liu is the author and co-author of >140 refereed journal publications, 9 book chapters and 68 conference presentations. Dr. Liu is also the inventor or co-inventor of 35 U.S. patents or patent applications. In 2009, Dr. Liu becomes the most-prolific author who has published in Bioconjugate Chemistry over the last 20 years. Dr. Liu’s contributions have significant impacts on several scientific areas, including inorganic chemistry, radiochemistry, radiopharmaceutical development, bioconjugates chemistry, molecular imaging, and nuclear medicine. Dr. Liu’s research has been supported by grants through the National Institute of Health, Department of Energy, American Heart Association and other awards from radiopharmaceutical companies. Over last 9 years at Purdue University, Dr. Liu has attracted >3.5 million dollars in grants from sponsors. In addition, Dr. Liu has filed 3 PCT applications at Purdue University.